Azoospermia Treatment in Nerul
Azoospermia treatment offers hope to men facing infertility challenges due to the absence of sperm in their semen. This condition, which affects about 1% of men, can be a significant barrier to conception. Dr. Prajna Shetty, a renowned Fertility Specialist in Nerul, provides advanced diagnostic and treatment options for men with azoospermia. Through personalized approaches like hormonal therapy, surgical sperm retrieval, and cutting-edge assisted reproductive technologies, Dr. Shetty’s clinic offers tailored solutions to address both obstructive and non-obstructive types of azoospermia. With a focus on understanding the root cause and offering effective treatments, men with azoospermia can find renewed hope for parenthood.
“Infertility isn’t just a medical condition—it’s an emotional journey that affects every aspect of a person’s life. With the right diagnosis, compassionate care, and advanced reproductive technologies, we can turn uncertainty into hope and help couples take confident steps toward parenthood.”
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What Is Azoospermia And How Does It Affect Fertility?
Azoospermia is a condition where there’s just no sperm in the ejaculate—none at all. So, when a man ejaculates, the semen comes out completely sperm-free, and since sperm are essential for fertilizing an egg, well, you can see the problem. It affects about 1% of men and is behind 10-15% of male infertility cases, which is more common than you might think.
There are really two main types. Obstructive azoospermia happens when sperm production is fine, but there’s a physical roadblock somewhere—could be in the testes, epididymis, or vas deferens—so the sperm just can’t make it into the semen.
Non-obstructive azoospermia is a bit trickier; here, the problem’s with sperm production itself. The testes either don’t make enough sperm or the sperm they do make aren’t viable.
Obviously, this hits fertility pretty hard. Without sperm, natural conception just doesn’t happen. But it’s not always a dead end—medical intervention can sometimes make a difference.
Most men with azoospermia don’t have any symptoms except, well, not being able to conceive. Occasionally, there might be other signs like:
- Low sex drive or trouble with erections
- Less body hair than expected
- Pain or swelling in the testicles
- Small or undescended testicles
- Hormonal issues
Diagnosis starts with a semen analysis to confirm the sperm are actually missing. From there, doctors might order hormone tests, genetic screening, or even a scrotal ultrasound to dig deeper. Figuring out whether it’s obstructive or non-obstructive is key, since it changes the treatment plan.
Luckily, modern medicine has come a long way. There are surgical sperm retrieval techniques, hormone-based treatments, and even advanced assisted reproduction like IVF with ICSI for couples who want to keep trying.
The Process Of Azoospermia Treatment At Dr. Prajna Shetty Fertility Clinic

Initial Consultation & Diagnosis
The process begins with a detailed review of medical history and a physical exam to identify any obvious signs of azoospermia. Diagnostic tests, including semen analysis, blood tests, genetic testing, and scrotal ultrasound, help confirm the diagnosis.

Treatment Plan Based on Diagnosis
Once the type of azoospermia (obstructive or non-obstructive) is determined, Dr. Shetty creates a personalized treatment plan to address the specific needs of the patient.

Sperm Retrieval Techniques:
For obstructive azoospermia, sperm retrieval is done through TESA (Testicular Sperm Aspiration), a simple procedure to extract sperm directly from the testes.

IVF & ICSI
If sperm is retrieved, Dr. Shetty’s team uses ICSI (Intracytoplasmic Sperm Injection) during IVF to fertilize eggs, ensuring that even a small number of viable sperm can lead to successful fertilization.

Ongoing Support & Compassionate Care
Patients receive continuous support and clear communication throughout the treatment process, ensuring they feel informed and cared for every step of the way.

Personalized Approach
Dr. Shetty tailors every treatment plan to the individual, avoiding a cookie-cutter approach to ensure the best possible outcome for each patient.
Causes Of Azoospermia And How It's Diagnosed
Azoospermia is a condition where a man’s ejaculate is devoid of sperm, affecting approximately 1% of men and up to 15% of those experiencing infertility.
It’s classified into two types:
Obstructive Azoospermia
Sperm is produced but blocked from being released.
The testes don’t produce enough sperm, or any at all.
Causes include:
Genetic conditions (e.g., Klinefelter syndrome)
Hormonal imbalances (testosterone, FSH, LH)
Infections, past surgeries, varicoceles, radiation, or chemicals.
Diagnosis
Diagnosis starts with semen analysis to confirm no sperm. Blood tests check hormone levels, and genetic tests assess chromosomal issues. A physical exam and ultrasound help detect blockages. Sometimes, a testicular biopsy is needed to determine whether the cause is obstructive or non-obstructive, guiding treatment.
Treatment Options For Azoospermia
Obstructive Azoospermia
Surgery (e.g., vasectomy reversal, microsurgery) to clear blockages.
Sperm retrieval techniques:
MESA, PESA, TESA.
Non-Obstructive Azoospermia
Hormonal treatments (e.g., clomiphene citrate, hCG, FSH) to stimulate sperm production.
Testicular sperm extraction (TESE) when sperm production is low.
Assisted Reproductive Technologies
IVF with ICSI: A single sperm is injected into the egg to bypass sperm count or motility issues.
Medical Management
Hypogonadotrophic Hypogonadism: hCG and FSH analogues can help in 80% of cases with 6 months of treatment.
Hormonal Optimization: Clomiphene citrate brings sperm back in 64.3% of patients; surgical sperm extraction works for those who need it.
Combined Protocols: Clomiphene, hCG, and hMG together get sperm back in 11% of cases, with successful surgical retrieval in 57%.
Cost Of Azoospermia Treatment In Nerul
A number of factors go into determining the cost of azoospermia treatment, including the type of azoospermia-it is either obstructive or non-obstructive-diagnostic tests that may be required, or specific treatment procedures involved, which also include sperm retrieval techniques. The addition of sophisticated procedures like Micro TESE, IVF with ICSI, or supplementary medications also tends to add to the overall cost.
At Dr. Shetty’s Fertility Clinic, we give an estimate of costs upfront and ensure flexible payment options to suit your needs with a personalized treatment plan. Our goal is to offer quality care while treatments are accessible and affordable
Why Choose Dr. Prajna Shetty For Azoospermia Treatment?
15+ Years of Fertility Expertise
Dr. Prajna Shetty has over 15 years of experience in reproductive medicine, specializing in complex infertility problems, such as male factor infertility and poor ovarian reserve.
Advanced Qualifications:
The qualifications include MBBS, DGO, DNB in Obstetrics & Gynaecology, and FNB in Reproductive Medicine to ensure expert care for her patients.
Specialization in Complex Fertility Cases:
Her areas of expertise include TESA for male factor infertility, recurrent pregnancy loss, and low ovarian reserve, all treated with tailored treatment plans.
Fertility Preservation & Oncofertility:
Dr. Shetty offers fertility preservation options to cancer patients, including egg and embryo freezing, to ensure that fertility is preserved before chemotherapy or surgery.
Dr. Shetty focuses on giving lucid, transparent counsel coupled with personalized support during the fertility journey.
Treatments are carried out at Cloudnine Hospital and her fully equipped clinic, offering advanced fertility services with a multidisciplinary team.
Frequently Asked Questions
What is the difference between obstructive and nonobstructive azoospermia?
Obstructive azoospermia describes blockage in the reproductive tract that inhibits sperm from being released into the semen, while nonobstructive azoospermia results from testicular failure to produce sperm.
How is azoospermia diagnosed?
Diagnosis can be made by semen analysis, which can confirm the absence of sperm in the ejaculate; other tests could include hormone evaluations and genetic testing that might uncover the underlying cause.
Is the medical treatment of azoospermia possible?
Medical treatment with medication may correct hormonal imbalances that, in some cases of nonobstructive azoospermia, result in improved sperm production, but obstructive cases are usually treated surgically.
What is the success rate with sperm retrieval techniques?
Success of sperm retrieval techniques depends on the underlying cause of azoospermia, with higher success rates related to obstructive, compared with nonobstructive forms.
How long does the treatment for azoospermia take?
Depending on the condition and stage of the treatment, different durations have been recorded for the treatment of azoospermia; sperm retrieval procedures can, however, be finished within some weeks to a few months.
Are there any life-style changes that I should make before treatment?
A healthy lifestyle, which includes a healthy diet, regular exercise, avoidance of alcohol and smoking, and control of stress, can significantly optimize fertility on its own and support the outcomes of treatment.


